Ferreira Lab, University of Georgia

Synthetic Methods, Natural Product Synthesis | Twitter: @TheFerreiraLab

Publications

50. The analysis of two distinct strategies toward the enantioselective formal total synthesis of (+)-Gelsenicine. Haofan Ji,† Phillip C. Knutson,† Christopher M. Harrington, Yan-Ting Ke, Eric M. Ferreira. Tetrahedron, 2023, 134, 133278. (Special issue in honor of Professor John Wood). 

49. Dearomative (3+2) Cycloadditions between Indoles and Vinyldiazo Species Enabled by a Red-Shifted Chromium Photocatalyst. Bradley K. Gall,† Avery K. Smith,† Eric M. Ferreira. Angew. Chem. Int. Ed. 2022, XX, XXXX-XXXX.

Screenshot 2022-10-11 192447

48. Multigram Synthesis of a Combustion-Relevant δ-Ketohydroperoxide through Sulfonylhydrazine Substitution. Yan-Ting Ke, Bradley K. Gall, Nicholas S. Dewey, Brandon Rotavera, Eric M. Ferreira. Chem. Eur. J. 2022, XX, XXXX-XXXX.

ytk

47. Chirality Transfer and Asymmetric Catalysis: Two Strategies toward the Enantioselective Formal Total Synthesis of (+)-Gelsenicine. Phillip C. Knutson,† Haofan Ji,† Christopher M. Harrington, Yan-Ting Ke, Eric M. Ferreira. Org Lett, 2022, 24, 4971-4976. 

ol-hjpck

46. Regioselectivity Influences in Platinum-Catalyzed Intramolecular Alkyne O-H and N-H Additions. Jeff P. Costello, Eric M. Ferreira. Org Lett. 2019, 21, 9934-9939.

FerreiraJeffPaper

45. Synthesis of 1,3-Diynes via Cadiot–Chodkiewicz Coupling of Volatile, in Situ Generated Bromoalkynes. Phillip C. Knutson, Haleigh E. Fredericks, Eric M. Ferreira. Org. Lett. 2018, 20, 6845-6849.

ol-2018-02975s_0009

44. Detection of an Energy-Transfer Pathway in Cr-Photoredox Catalysis. Robert F. Higgins, Steven M. Fatur, Niels H. Damrauer, Eric M. Ferreira, Anthony K. Rappé, and Matthew P. Shores. ACS Catal. 2018, 8, 9216.

cs-2018-030138_0011

43. Cyclopentene Annulations of Alkene Radical Cations with Vinyl Diazo Species Using Photocatalysis. Francisco J. Sarabia,† Qiankun Li,† and Eric M. Ferreira. Angew. Chem. Int. Ed. 2018, 130, 11181.

Presentation1

42. Establishment of Novel Biosynthetic Pathways for the Production of Salicyl Alcohol and Gentisyl Alcohol in Engineered Escherichia coli. Xiaolin Shen, Jia Wang, Bradley K. Gall, Eric M. Ferreira, Qipeng Yuan, and Yajun Yan. ACS Synth. Biol., 2018, 7, 1012–1017.

sb-2018-00051y_0005

41. Engineering a bacterial platform for total biosynthesis of caffeic acid derived phenethyl esters and amides. Jian Wang, Monika Mahajani, Sheneika L. Jackson,  Yaping Yang, Mengyin Chen, Eric M .Ferreira,  Yuheng Lin, and Yajun Yan. Metabolic Engineering, 2017, 44, 89–99.

Untitled picture

40. Meta-Selective C−H Arylation of Aromatic Alcohols with a Readily Attachable and Cleavable Molecular Scaffold. Chem. Eur. J2017, 23, 11519 – 11523.

Untitled picture

39. Radical Cation Cyclopropanations via Chromium Photooxidative Catalysis. Francisco J. Sarabia and Eric M. Ferreira. Org. Lett. 2017192865–2868.

ol-2017-010959_0011

38. A boron-based Ireland-Claisen approach to the synthesis of pordamacrine A. Curtis A. Seizert and Eric M. Ferreira. Tetrahedron, 2016, 73, 4186-4194.

1-s2.0-S0040402016311851-fx1

37. Platinum-Catalyzed α,β-Unsaturated Carbene Formation in the Formal Syntheses of Frondosin B and LiphagalKhoi Q. Huynh, Curtis A. Seizert, Tarik J. Ozumerzifon, Paul A. Allegretti, and Eric M. Ferreira. Org. Lett., 2017, 19, 294–297.

ol-2016-036824_0010 (1)

36. Chromium photocatalysis: accessing structural complements to Diels–Alder adducts with electron-deficient dienophiles. Stevenson, Susan M.; Higgins, Robert F.; Shores, Matthew P. J.; Ferreira, Eric M. Chem. Sci., 2016, 8, 654–660.

ga

35. Palladium(II)-Catalyzed ortho-Arylation of Aromatic Alcohols with a Readily Attachable and Cleavable Molecular Scaffold. Li, Qiankun; Knight, Brian J.; Ferreira, Eric M. Chem. Eur. J. 2016, 22, 13054 –13058. Highlighted in Chemistry Views!

Untitled picture

Untitled picture

34. C–C bond migration in the cycloisomerization of 1,6-enynes. Stevenson, Susan M.; Newcomb, Eric T.; Ferreira, Eric M. Org. Chem. Front. 2016, 3, 1228-1235.

SuzFULLPAPER - Copy

33. Uncovering the Roles of Oxygen in Cr(III) Photoredox Catalysis. Higgins, Robert F.; Fatur, Steven M.; Shepard, Samual G.; Stevenson, Susan M.; Boston, David B.; Ferreira, Eric M.; Damrauer, Niels H.; Rappé, Anthony K.; Shores, Matthew P. J. Am. Chem. Soc. 2016, 138, 5451-5464.

suzie cclear o2 paper

32. Total Synthesis of Gelsenicine via a Catalyzed Cycloisomerization Strategy. Newcomb, Eric T.; Knutson, Phil C.; Pedersen, Blaine A.; Ferreira, Eric M. J. Am. Chem. Soc. 2016, 138, 108-111. Highlighted in Synfacts!

ja-2015-12263t_0007

31. Lewis Acid Mediated Vinylogous Additions of Enol Nucleophiles into an α,β-Unsaturated Platinum Carbene. Allegretti, Paul A.; Huynh, Khoi; Ozumerzifon, Tarik J.; Ferreira, Eric M. Org. Lett. 2016, 18, 64-67.

khoi pic

30. The Design of a Readily Attachable and Cleavable Molecular Scaffold for ortho-Selective C–H Alkenylation of Arene Alcohols. Knight, Brian J.; Rothbaum, Jacob O.; Ferreira, Eric M.  Chem. Sci. 2016, 7, 1982-1987.

brian, jake pic

29. An analysis of the complementary stereoselective alkylations of imidazolidinone derivatives toward α-quaternary proline-based amino amides. Knight, Brian J.; Stache, Erin E.; Ferreira, Eric M. Tetrahedron 2015, 71, 5814-5823.

28. Photooxidizing Chromium Catalysts for Promoting Radical Cation Cycloadditions. Stevenson, Susan M.; Shores, Matthew P.; Ferreira, Eric M. Angew. Chem. Int. Ed. 2015, 54, 6506-6510.

mcontent

27. An analysis of the influences dictating regioselectivity in platinum-catalyzed hydrosilylations of internal alkynes. Rooke, Douglas A.; Menard, Zachary A.; Ferreira, Eric M. Tetrahedron 2014, 70, 4232-4244. (Special issue in honor of Tetrahedron Young Investigator Professor Sarah Reisman)

1-s2.0-S0040402014003184-fx1

26. An Examination of the Scope and Stereochemistry of the Ireland-Claisen Rearrangement of Boron Ketene Acetals. Seizert, Curtis A.; Ferreira, Eric M. Chem. Eur. J. 2014, 20, 4460-4468.

mcontent_2

25. Complementary Stereochemical Outcomes in Proline-Based Self-Regenerations of Stereocenters.  Knight, Brian J.; Stache, Erin E.; Ferreira, Eric M. Org. Lett. 2014, 16, 432-435.

droppedImage_3

24. C–C bond migration in the cycloisomerization of oxygen-tethered 1,6-enynes. Stevenson, Susan M.; Newcomb, Eric T.; Ferreira, Eric M. Chem. Comm. 2014, 50, 5239-5241. (Emerging Investigators Issue).

droppedImage_2

23. Vicinal Bisheterocyclizations of Alkynes via Nucleophilic Interception of a Catalytic Platinum Carbene. Allegretti, Paul A.; Ferreira, Eric M. J. Am. Chem. Soc. 2013, 135, 17266-17269. Highlighted in Synfacts! Cited in a column on the Organic Chemistry Portal!

droppedImage_1

22. Stereoselective Synthesis of Tetrasubstituted Olefins through a Halogen-Induced 1,2-Silyl Migration. Barczak, Nicholas T.; Rooke, Douglas A.; Menard, Zachary A.; Ferreira, Eric M. Angew. Chem. Int. Ed. 2013, 52, 7579-7582. Chosen by the Editors as a Hot Paper! Highlighted in Synfacts!

mcontent_1

21. Use of a Palladium(II)-Catalyzed Oxidative Kinetic Resolution in Synthetic Efforts toward Bielschowskysin. Meyer, Michael E.; Phillips, John H.; Ferreira, Eric M.; Stoltz, Brian M. Tetrahedron  2013, 69, 7627-7635. 

20. Highly Enantiospecific Platinum-Catalyzed Cycloisomerizations: Synthesis of Enantioenriched Oxabicyloheptene Derivatives. Newcomb, Eric T.; Ferreira, Eric M. Org. Lett. 2013, 15, 1772-1775. Highlighted in Synfacts! Cited in a column on the Organic Chemistry Portal!

ol-2013-00625f_0011

19. Platinum-Catalyzed Cyclizations via Carbene Intermediates: Synthesis of Complementary Positional Isomers of Isoxazoles. Allegretti, Paul A.; Ferreira, Eric M. Chem. Sci. 2013, 4, 1053-1058.

droppedImage

18. Palladium-Catalyzed Hiyama Couplings of α-Silylenoates and α-Silylenamides. Rooke, Douglas A.; Ferreira, Eric M. Org. Lett. 2012, 14, 3328-3331. Highlighted in Synfacts!

ol-2012-01300r_0001

17. Molecular Scaffolds with Remote Directing Groups for Selective Palladium-Catalyzed C-H Bond Functionalizations. Stache, Erin E.; Seizert, Curtis A.; Ferreira, Eric M. Chem. Sci. 2012, 3, 1623-1628.

GA

16. Platinum-Catalyzed Hydrosilylations of Internal Alkynes: Harnessing Substituent Effects to Achieve High Regioselectivity. Rooke, Douglas A.; Ferreira, Eric M. Angew. Chem. Int. Ed. 2012, 51, 3225-3230.

mcontent

15. Generation of α,β-Unsaturated Platinum Carbenes from Homopropargylic Alcohols: Rearrangements to Polysubstituted Furans. Allegretti, Paul A.; Ferreira, Eric M. Org. Lett. 2011, 13, 5924-5927. Highlighted on the Organic Chemistry Portal!

ol-2011-02649j_0005

14. Stereoselective Syntheses of Trisubstituted Olefins via Platinum Catalysis: α-Silylenones with Geometrical Complementarity. Rooke, Doug A.; Ferreira, Eric M. J. Am. Chem. Soc. 2010, 132, 11926-11928. Featured on the Organic Chemistry Portal!

ja-2010-058197_0009


13. Differential Reactivities of Enyne Substrates in Ruthenium- and Palladium-Catalyzed Cycloisomerizations. Trost, Barry M.; Gutierrez, Alicia C.; Ferreira, Eric M. J. Am. Chem. Soc. 2010, 132, 9206-9218. 

12. The Palladium-Catalyzed Aerobic Kinetic Resolution of Secondary Alcohols: Reaction Development, Scope, and Applications. Ebner, David C.; Bagdanoff, Jefferey T.; Ferreira, Eric M.; McFadden, Ryan M.; Caspi, Daniel D.; Trend, Raissa M.; Stoltz, Brian M. Chem. Eur. J. 2009, 15, 12878-12992.

11. C-H Bond Functionalizations with Palladium(II): Intramolecular Oxidative Annulations of Arenes. Ferreira, Eric M.; Zhang, Haiming; Stoltz, Brian M. Tetrahedron 2008, 64, 5987-6001.

10. Ruthenium- and Palladium-Catalyzed Enyne Cycloisomerizations: Differentially Stereoselective Syntheses of Bicyclic Structures. Trost, Barry M.; Ferreira, Eric M.; Gutierrez, Alicia C. J. Am. Chem. Soc. 2008, 130, 16176-16177.

9. Convergency and Divergency as Strategic Elements in Total Synthesis: the Total Synthesis of (-)-drupacine and the Formal Total Synthesis of (+/-)-cephalotaxine, (-)-cephalotaxine, and (+)-cephalotaxine. Liu, Qi; Ferreira, Eric M.; Stoltz, Brian M. J. Org. Chem. 2007, 72, 7352-7358.

8. 2-Diazoacetoacetic Acid, an Efficient and Convenient Reagent for the Synthesis of α-diazo-β-Keto Esters. Meyer, Michael E.; Ferreira, Eric M.; Stoltz, Brian M. Chem. Comm. 2006, 12, 1316-1318.

7. The Synthesis of C(3β) Functionalized Indoles Via Hydroboration/Suzuki-Miyaura Coupling Sequence. Ferreira, Eric M.; Stoltz, Brian M. Tetrahedron Letters 2006, 47, 8579-8582.

6. Direct Oxidative Heck Cyclizations: Intramolecular Fujiwara-Moritani Arylations for the Synthesis of Functionalized Benzofurans and Dihydrobenzofurans. Zhang, Haiming; Ferreira, Eric M.; Stoltz, Brian M. Angew. Chem. Int. Ed. 2004, 43, 6144-6148.

5. Catalytic C-H Bond Functionalization with Palladium(II): Aerobic Oxidative Annulations of Indoles. Ferreira, Eric M.; Stoltz, Brian M. J. Am. Chem. Soc. 2003, 125, 9578-9579.

4. Palladium-Catalyzed Enantioselective Oxidation of Alcohols: a Dramatic Rate Acceleration by Cs2CO3/t-BuOH. Bagdanoff, Jeffrey T.; Ferreira, Eric M.; Stoltz, Brian M. Org. Lett. 2003, 5, 835-837.

3. Palladium-Catalyzed Oxidative Wacker Cyclizations in Nonpolar Organic Solvents with Molecular Oxygen: A Stepping Stone to Asymmetric Aerobic Cyclizations. Trend, Raissa M.; Ramtohul, Yeeman K.; Ferreira, Eric M.; Stoltz, Brian M. Angew. Chem. Int. Ed. 2003, 42, 2892-2895.

2. The Palladium-Catalyzed Oxidative Kinetic Resolution of Secondary Alcohols with Molecular Oxygen. Ferreira, Eric M.; Stoltz, Brian M. J. Am. Chem. Soc. 2001, 123, 7725-7726.

1. Asymmetric Conjugate Reduction of α,β-unsaturated Esters Using a Chiral Phosphine-Copper Catalyst. Appella, Daniel H.; Moritani, Yasunori; Shintani, Ryo; Ferreira, Eric M.; Buchwald, Stephen L. J. Am. Chem. Soc. 1999, 121, 9473-9474.