Ferreira Lab, University of Georgia

Synthetic Methods, Natural Product Synthesis

Publications

40. Engineering a bacterial platform for total biosynthesis of caffeic acid derived phenethyl esters and amides. JianWang, MonikaMahajani, Sheneika L.Jackson,  YapingYang, MengyinChen, Eric M.Ferreira,  YuhengLin, and YajunYan. Metabolic Engineering, 2017, 44, 89–99.

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39. Radical Cation Cyclopropanations via Chromium Photooxidative Catalysis. Francisco J. Sarabia and Eric M. Ferreira. Organic Letters2017, ASAP.

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38. A boron-based Ireland-Claisen approach to the synthesis of pordamacrine A. Curtis A. Seizert and Eric M. Ferreira. Tetrahedron, 2016, In Press.

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37. Platinum-Catalyzed α,β-Unsaturated Carbene Formation in the Formal Syntheses of Frondosin B and LiphagalKhoi Q. Huynh, Curtis A. Seizert, Tarik J. Ozumerzifon, Paul A. Allegretti, and Eric M. Ferreira. Org. Lett., 2017, 19, 294–297.

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36. Chromium photocatalysis: accessing structural complements to Diels–Alder adducts with electron-deficient dienophiles. Stevenson, Susan M.; Higgins, Robert F.; Shores, Matthew P. J.; Ferreira, Eric M. Chem. Sci., 2016, 8, 654–660.

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35. Palladium(II)-Catalyzed ortho-Arylation of Aromatic Alcohols with a Readily Attachable and Cleavable Molecular Scaffold. Li, Qiankun; Knight, Brian J.; Ferreira, Eric M. Chem. Eur. J. 2016, 22, 13054 –13058. Highlighted in Chemistry Views!

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34. C–C bond migration in the cycloisomerization of 1,6-enynes. Stevenson, Susan M.; Newcomb, Eric T.; Ferreira, Eric M. Org. Chem. Front. 2016, 3, 1228-1235.

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33. Uncovering the Roles of Oxygen in Cr(III) Photoredox Catalysis. Higgins, Robert F.; Fatur, Steven M.; Shepard, Samual G.; Stevenson, Susan M.; Boston, David B.; Ferreira, Eric M.; Damrauer, Niels H.; Rappé, Anthony K.; Shores, Matthew P. J. Am. Chem. Soc. 2016, 138, 5451-5464.

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32. Total Synthesis of Gelsenicine via a Catalyzed Cycloisomerization Strategy. Newcomb, Eric T.; Knutson, Phil C.; Pedersen, Blaine A.; Ferreira, Eric M. J. Am. Chem. Soc. 2016, 138, 108-111. Highlighted in Synfacts!

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31. Lewis Acid Mediated Vinylogous Additions of Enol Nucleophiles into an α,β-Unsaturated Platinum Carbene. Allegretti, Paul A.; Huynh, Khoi; Ozumerzifon, Tarik J.; Ferreira, Eric M. Org. Lett. 2016, 18, 64-67.

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30. The Design of a Readily Attachable and Cleavable Molecular Scaffold for ortho-Selective C–H Alkenylation of Arene Alcohols. Knight, Brian J.; Rothbaum, Jacob O.; Ferreira, Eric M.  Chem. Sci. 2016, 7, 1982-1987.

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29. An analysis of the complementary stereoselective alkylations of imidazolidinone derivatives toward α-quaternary proline-based amino amides. Knight, Brian J.; Stache, Erin E.; Ferreira, Eric M. Tetrahedron 2015, 71, 5814-5823.

28. Photooxidizing Chromium Catalysts for Promoting Radical Cation Cycloadditions. Stevenson, Susan M.; Shores, Matthew P.; Ferreira, Eric M. Angew. Chem. Int. Ed. 2015, 54, 6506-6510.

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27. An analysis of the influences dictating regioselectivity in platinum-catalyzed hydrosilylations of internal alkynes. Rooke, Douglas A.; Menard, Zachary A.; Ferreira, Eric M. Tetrahedron 2014, 70, 4232-4244. (Special issue in honor of Tetrahedron Young Investigator Professor Sarah Reisman)

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26. An Examination of the Scope and Stereochemistry of the Ireland-Claisen Rearrangement of Boron Ketene Acetals. Seizert, Curtis A.; Ferreira, Eric M. Chem. Eur. J. 2014, 20, 4460-4468.

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25. Complementary Stereochemical Outcomes in Proline-Based Self-Regenerations of Stereocenters.  Knight, Brian J.; Stache, Erin E.; Ferreira, Eric M. Org. Lett. 2014, 16, 432-435.

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24. C–C bond migration in the cycloisomerization of oxygen-tethered 1,6-enynes. Stevenson, Susan M.; Newcomb, Eric T.; Ferreira, Eric M. Chem. Comm. 2014, 50, 5239-5241. (Emerging Investigators Issue).

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23. Vicinal Bisheterocyclizations of Alkynes via Nucleophilic Interception of a Catalytic Platinum Carbene. Allegretti, Paul A.; Ferreira, Eric M. J. Am. Chem. Soc. 2013, 135, 17266-17269. Highlighted in Synfacts! Cited in a column on the Organic Chemistry Portal!

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22. Stereoselective Synthesis of Tetrasubstituted Olefins through a Halogen-Induced 1,2-Silyl Migration. Barczak, Nicholas T.; Rooke, Douglas A.; Menard, Zachary A.; Ferreira, Eric M. Angew. Chem. Int. Ed. 2013, 52, 7579-7582. Chosen by the Editors as a Hot Paper! Highlighted in Synfacts!

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21. Use of a Palladium(II)-Catalyzed Oxidative Kinetic Resolution in Synthetic Efforts toward Bielschowskysin. Meyer, Michael E.; Phillips, John H.; Ferreira, Eric M.; Stoltz, Brian M. Tetrahedron  2013, 69, 7627-7635. 

20. Highly Enantiospecific Platinum-Catalyzed Cycloisomerizations: Synthesis of Enantioenriched Oxabicyloheptene Derivatives. Newcomb, Eric T.; Ferreira, Eric M. Org. Lett. 2013, 15, 1772-1775. Highlighted in Synfacts! Cited in a column on the Organic Chemistry Portal!

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19. Platinum-Catalyzed Cyclizations via Carbene Intermediates: Synthesis of Complementary Positional Isomers of Isoxazoles. Allegretti, Paul A.; Ferreira, Eric M. Chem. Sci. 2013, 4, 1053-1058.

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18. Palladium-Catalyzed Hiyama Couplings of α-Silylenoates and α-Silylenamides. Rooke, Douglas A.; Ferreira, Eric M. Org. Lett. 2012, 14, 3328-3331. Highlighted in Synfacts!

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17. Molecular Scaffolds with Remote Directing Groups for Selective Palladium-Catalyzed C-H Bond Functionalizations. Stache, Erin E.; Seizert, Curtis A.; Ferreira, Eric M. Chem. Sci. 2012, 3, 1623-1628.

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16. Platinum-Catalyzed Hydrosilylations of Internal Alkynes: Harnessing Substituent Effects to Achieve High Regioselectivity. Rooke, Douglas A.; Ferreira, Eric M. Angew. Chem. Int. Ed. 2012, 51, 3225-3230.

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15. Generation of α,β-Unsaturated Platinum Carbenes from Homopropargylic Alcohols: Rearrangements to Polysubstituted Furans. Allegretti, Paul A.; Ferreira, Eric M. Org. Lett. 2011, 13, 5924-5927. Highlighted on the Organic Chemistry Portal!

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14. Stereoselective Syntheses of Trisubstituted Olefins via Platinum Catalysis: α-Silylenones with Geometrical Complementarity. Rooke, Doug A.; Ferreira, Eric M. J. Am. Chem. Soc. 2010, 132, 11926-11928. Featured on the Organic Chemistry Portal!

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13. Differential Reactivities of Enyne Substrates in Ruthenium- and Palladium-Catalyzed Cycloisomerizations. Trost, Barry M.; Gutierrez, Alicia C.; Ferreira, Eric M. J. Am. Chem. Soc. 2010, 132, 9206-9218. 

12. The Palladium-Catalyzed Aerobic Kinetic Resolution of Secondary Alcohols: Reaction Development, Scope, and Applications. Ebner, David C.; Bagdanoff, Jefferey T.; Ferreira, Eric M.; McFadden, Ryan M.; Caspi, Daniel D.; Trend, Raissa M.; Stoltz, Brian M. Chem. Eur. J. 2009, 15, 12878-12992.

11. C-H Bond Functionalizations with Palladium(II): Intramolecular Oxidative Annulations of Arenes. Ferreira, Eric M.; Zhang, Haiming; Stoltz, Brian M. Tetrahedron 2008, 64, 5987-6001.

10. Ruthenium- and Palladium-Catalyzed Enyne Cycloisomerizations: Differentially Stereoselective Syntheses of Bicyclic Structures. Trost, Barry M.; Ferreira, Eric M.; Gutierrez, Alicia C. J. Am. Chem. Soc. 2008, 130, 16176-16177.

9. Convergency and Divergency as Strategic Elements in Total Synthesis: the Total Synthesis of (-)-drupacine and the Formal Total Synthesis of (+/-)-cephalotaxine, (-)-cephalotaxine, and (+)-cephalotaxine. Liu, Qi; Ferreira, Eric M.; Stoltz, Brian M. J. Org. Chem. 2007, 72, 7352-7358.

8. 2-Diazoacetoacetic Acid, an Efficient and Convenient Reagent for the Synthesis of α-diazo-β-Keto Esters. Meyer, Michael E.; Ferreira, Eric M.; Stoltz, Brian M. Chem. Comm. 2006, 12, 1316-1318.

7. The Synthesis of C(3β) Functionalized Indoles Via Hydroboration/Suzuki-Miyaura Coupling Sequence. Ferreira, Eric M.; Stoltz, Brian M. Tetrahedron Letters 2006, 47, 8579-8582.

6. Direct Oxidative Heck Cyclizations: Intramolecular Fujiwara-Moritani Arylations for the Synthesis of Functionalized Benzofurans and Dihydrobenzofurans. Zhang, Haiming; Ferreira, Eric M.; Stoltz, Brian M. Angew. Chem. Int. Ed. 2004, 43, 6144-6148.

5. Catalytic C-H Bond Functionalization with Palladium(II): Aerobic Oxidative Annulations of Indoles. Ferreira, Eric M.; Stoltz, Brian M. J. Am. Chem. Soc. 2003, 125, 9578-9579.

4. Palladium-Catalyzed Enantioselective Oxidation of Alcohols: a Dramatic Rate Acceleration by Cs2CO3/t-BuOH. Bagdanoff, Jeffrey T.; Ferreira, Eric M.; Stoltz, Brian M. Org. Lett. 2003, 5, 835-837.

3. Palladium-Catalyzed Oxidative Wacker Cyclizations in Nonpolar Organic Solvents with Molecular Oxygen: A Stepping Stone to Asymmetric Aerobic Cyclizations. Trend, Raissa M.; Ramtohul, Yeeman K.; Ferreira, Eric M.; Stoltz, Brian M. Angew. Chem. Int. Ed. 2003, 42, 2892-2895.

2. The Palladium-Catalyzed Oxidative Kinetic Resolution of Secondary Alcohols with Molecular Oxygen. Ferreira, Eric M.; Stoltz, Brian M. J. Am. Chem. Soc. 2001, 123, 7725-7726.

1. Asymmetric Conjugate Reduction of α,β-unsaturated Esters Using a Chiral Phosphine-Copper Catalyst. Appella, Daniel H.; Moritani, Yasunori; Shintani, Ryo; Ferreira, Eric M.; Buchwald, Stephen L. J. Am. Chem. Soc. 1999, 121, 9473-9474.

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